This paper tried to use the human capitals playing actual role to analyze their effect on regional economic development. According to the results,after reform and opening-up,the structure of China's different categories of human capital kept stable; five categories of human capital were correlated strongly and had very high explanatory power for regional economy; human capitals corresponding to the primary,secondary and tertiary industries also had high explanatory ability for the industries'added value. This new method is more scientific for the analysis on the relationship between human capital and regional economy.