The west big development is the deep open in the west. No other than to enlarge the openness, the strategy target of the west big development can be achieved. The west big development is faced with unprecedented good international and domestic environment. This paper analyzes the education quality of the human resources in the west region, the problem of shortage of human resources, and proposes tha the strategy on human resources development in the west should be focus on education, how to keep human resources and introduce human resources into the west.